邢唷> hkg欹a 騍bjbj[[*Z9bE\9bE\  kkkkk8L<c<"?UUUU;;;;;;;>;AF;k;kkUUB<+,+,+, kUkU;+,;+,+,6h47Up鲄禠懷W(6z;3<0c<6丄*丄 4747丄k8|+,;;+,c<丄 I 1: 擽ZO&O {哠蔛褃xb済 '`+R: sY l蟚: Il蟚 鶴ut^g:1987t^6g ?e籰b棇: -NqQZQXT5uP[異眥 HYPERLINK "mailto:yilunying@ecust.edu.cn" yilunying@ecust.edu.cn T鹼5u輯13321957115T軂0W@W Nwm^卙G栵130鱏瀃寶踁|i203異200237 Ye瞼蟸哠 2005t^9g髞2009t^6g NSNt錧'Yf[ Sf[NRP[錧 zf[b 緗苸S錧NN 錧f[f[隭 2009t^9g髞2014t^6g NSNt錧'Yf[ Sf[NRP[錧 zf[b R恎Sf[NN tf[ZS隭 2014t^2g髞2014t^6g 駛齎University of Birmingham Sf[b TT鵚{Q 錧\O蟸哠: 2014t^7g 髞 蔔 NSNt錧'Yf[ Sf[NRP[錧 zf[b f[褃ZS隭T 黐^ O癳誵Ye坈 穬VYN翄fN 2011t^ eQ 怤SNt錧'Yf[ OZS鵚瞼R 2011t^ NSNt錧'Yf[  ?栄y泂 VYf[褢 2012t^ 齎禰Ye瞼钀  ZS隭xvzu齎禰VYf[褢 2012t^ Nwm^xvzuf[/g簨[W訷XTO 2012t^ Nwm^xvzuf[/g簨[W鉙4YJTNI{VY 2013t^ NSNt錧'Yf[  NS  VYf[褢 2013t^ NSNt錧'Yf[坈圢 O纘f[u 饄鱏 2014t^ NSNt錧'Yf[坈圢 2014J\c儔娬kNu 饄鱏 2015t^ -N齎褃f[b/gOSO坈圢 *gegsY褃f[禰VY 2016t^ 'k眱艝-TT齎Ye褃噀膥莮坈圢 NLugwQ\o汻sY褃f[禰VY 簨噀Rh 褟擭t^ 3u鲖篘騗(WNat. Nanotechnol. (1莧)0 Sci. Rep. (1莧)0Chem. Commun. (5莧)0Anal. Chem. (5莧)0Small (1莧)I{SCIg R N裇h埡媷e29莧IF>5: 20莧 vQ-N,{N\O噀鄗7莧 惎媆O噀鄗4莧 \b棁e鄗6莧 諲_287!k wQSO俌 N ZS隭g魰裇h埡媷e Yi-Lun Ying, Junji Zhang, Rui Gao, Yi-Tao Long*.  Nanopore-based sequencing and detection of nucleic acids. Angew. Chem. Int. Ed., 2013, 52, 13154-13161. (IF = 14.107, Cited by 39) Yi-Lun Ying, Hai-Yan Wang, Sutherland Todd C, Yi-Tao Long*. 揗onitoring of an ATP-binding aptamer and its conformational changes using an alpha-hemolysin nanopore. Small, 2011, 7, 87-94. (IF = 8.368, Cited by 38) Yi-Lun Ying, Da-Wei Li, Yu Liu, Dey Subrata K, Kraatz Heinz-Bernhard, Yi-Tao Long*. 揜ecognizing the translocation signals of individual peptide-oligonucleotide conjugates using an alpha-hemolysin nanopore. Chemical Communications, 2012, 48, 8784-8786. (IF = 6.834, Cited by 11) Yi-Lun Ying, Da-Wei Li, Li Yang, Lee Jeremy S, Yi-Tao Long*. 揈nhanced translocation of poly(dT)45 through an alpha-hemolysin nanopore by binding with antibody. Chemical Communications, 2011, 47, 5690-5692. (IF = 6.834, Cited by 15) Yi-Lun Ying, Junjiv Zhang, Fu-Na Meng, Chan Cao, Xuyang Yao, Willner Itamar, He Tian*, Yi-Tao Long*. 揂 stimuli-responsive nanopore based on a photoresponsive host-guest system, Scientific Reports. 2013, 3, 1662-1662. (IF = 5.578, Cited by 22) 擽ZO&O _f R皵 泤鵽 Ng*m梘 櫉縉沵*.  硚s|怱怳SRP[纇KmP53藛}vNDNA剉1_鴙扤\O(u Sf[f[ 2013 71, 44-50. (IF = 0.611, Cited by 2) Wei Ma, Yi-Lun Ying, Lixia Qin., Zhen Gu, Hao Zhou, Da-Wei Li, Sutherland Todd C., Yi-Tao Long.  Investigating electron-transfer processes using a biomimetic hybrid bilayer membrane system. Nature protocols, 2013, 8, 439-450. (IF = 9.673, Cited by 18) Yu Liu; Yi-Lun Ying; Hai-Yan Wang, Chan Cao, Da-Wei Li, Wen-Qing Zhang, Yi-Tao Long*. 揜eal-time monitoring of the oxidative response of a membrane-channel biomimetic system to free radicals. Chemical Communications, 2013, 49, 6584-6586. (IF = 6.834, Cited by 0) Chao Jing, Zhen Gu, Yi-Lun Ying, Da-Wei Li, Lei Zhang, Yi-Tao Long*. 揅hrominance to dimension: A real-time method for measuring the size of single gold nanoparticles. Analytical chemistry, 2012, 84, 4284-4291. (IF = 5.636, Cited by 28) Hai-Yan Wang, Yi-Lun Ying, Yang Li, Kraatz Heinz-Bernhard, Yi-Tao Long*. 揘anopore analysis of beta-amyloid peptide aggregation transition induced by small molecules. Analytical Chemistry, 2011, 83, 1746-1752. (IF = 5.636, Cited by 50) Xiuwen Wang, Wei Ma, Yi-Lun Ying, Jie Liang, Yi-Tao Long *. 揃is coenzyme Q0: synthesis, characteristics, and application. Chemistry-an Asian Journal, 2011, 6. 1064-1076. (IF = 4.596, Cited by 1) Wei Ma, Hao Zhou, Yi-Lun Ying, Da-Wei Li, Guorong Chen, Yi-Tao Long*, Chen Hongyuan.  In situ spectroeletrochemistry and cytotoxic activities of natural ubiquinone analogues. Tetrahedron, 2011, 67, 5990-6000. (IF = 2.641, Cited by 9) ZSTg魰裇h埡媷e Fu-Na Meng, Xuyang Yao, Yi-Lun Ying*, Junji Zhang, He Tian, Yi-Tao Long*.  Single-molecule analysis of the self-assembly process facilitated by host-guest interactions. Chem. Commun. 2015, 51, 1202-1205. (IF = 6.834, Cited by 5) Yongxu Hu, Yi-Lun Ying*, Zhen Gu, Chan Cao, Bing-Yong Yan, Hui-Feng Wang, Yi-Tao Long*. 揝ingle molecule study of initial structural features on the amyloidosis process. Chem. Commun. 2016, DOI: 10.1039/c6cc01292b. (IF = 6.834, Cited by 0) Yue Cao, Yao Lin, Ruo-Can Qian*, Yi-Lun Ying*, Wei Si, Jingjie Sha*, Yunfei Chen, Yi-Tao Long*. 揈vidence of single-nanoparticle translocation through solid-state nanopore by plasmon resonance energy transfer. Chem. Commun. 2016, 52, 5230-5233. (IF = 6.834, Cited by 0) Rui Gao, Yi-Lun Ying*, Bing-Yong Yan, Parvez Iqbal, Jon A. Preece, Xinyan Wu. 揢ltrasensitive determination of mercury (ii) using glass nanopores functionalized with macrocyclic dioxotetraamines Microchim. Acta, 2015, 183, 491-495. (IF = 3.741, Cited by 1) Yi-Lun Ying, Chan Cao, Yi-Tao Long*. 揝ingle molecule analysis by biological nanopore sensors. Analyst, 2014, 139, 3826-3835. . (IF = 6.834, Cited by 13) Chan Cao, Yi-Lun Ying, Zheng-Li Hu, Dong-Fang Liao, He Tian, Yi-Tao Long*. 揇iscrimination of Oligonucleotides of Different Length with a Wild-Type Aerolysin Nanopore. Nat Nanotechnol., 2016, accepted. (IF = 34.048, Cited by 0) Xing Zhang, Junji Zhang*, Yi-Lun Ying, He Tian, Yi-Tao Long*. 揝ingle molecule analysis of light-regulated RNA:spiropyran interactions. Chemical Science, 2014, 5, 2642-2646. (IF = 9.215, Cited by 12) Zhen Gu, Chao Jing, Yi-Lun Ying, Pin-Gang He, Yi-Tao Long*. 揑n situ high throughput scattering light analysis of single plasmonic nanoparticles in living cells. Theranostics, 2014, 5, 188-195. (IF = 7.827, Cited by 4) Xin Shi, Haowen Li, Yi-Lun Ying, Chang Liu, Li Zhang, Yi- Tao Long. 揑n situ monitoring of catalytic process variations in a single nanowire by dark-field-assisted surface-enhanced Raman spectroscopy." Chemical Communications, 2016, 52, 1044-1047. (IF = 6.834, Cited by 0) Zhen Gu, Yi-Lun Ying, Chan Cao, Pingang He, Yi-Tao Long*. 揜eply to comment on 揂ccurate data process for nanopore analysis. Analytical Chemistry, 2015, 87, 1065310656. (IF = 5.636, Cited by 0) Zhen Gu, Yi-Lun Ying, Chan Cao, Pingang He, Yi-Tao Long*. 揂ccurate data process for nanopore analysis. Analytical Chemistry, 2015, 87, 907-913. (IF = 5.636, Cited by 8) Chan Cao, Yi-Lun Ying, Zhen Gu, Yi-Tao Long*. 揈nhanced resolution of low molecular weight poly(ethylene glycol) in nanopore analysis. Analytical Chemistry, 2014, 86, 11946-11950. (IF = 5.636, Cited by 2) Xin Shi, Rui Gao, Yi-Lun Ying, Wei Si, Yunfei Chen, Yi-Tao Long*. 揝ingle Molecule Microscopy: An integrated system for optical and electrical detection of single molecules/particles inside a solid-state nanopore. Faraday Discussions, 2015, 184, 85-99. (IF = 4.606, Cited by 0) Rui Gao, Yi-Lun Ying, Bing-Yong Yan, Yi-Tao Long*. 揂n integrated current measurement system for nanopore analysis. Chinese Science Bulletin, 2014, 59, 4968-4973. (IF = 1.633, Cited by 9) Na Zhang, Yongxu Hu, Zhen Gu, Yi-Lun Ying, Pin-Gang He*, Yi-Tao Long*. 揂n integrat",.24TVjnvxz $ & . H J v x 檠榻瘮償僼償蒋斀`'h!5h&5丅*OJQJ\乛Jphh!5h470JOJQJ^J!jh!5h47OJQJU^Jh!5h47OJQJ^Jh!5hi5丱JQJ^Jh!5h475丱JQJ^J'h!5h475丅*OJQJ]乛Jph.h!5hi5丅*CJ OJQJ]乛Jo(ph+h!5h475丅*CJ OJQJ]乛JphVln& H }n$dh$Ifa$gd鬽ibkd$$If杔0b } t644 lapyti dh$Ifgd]// dh$Ifgd鬽i$a$gd47H J x /-bkd$$If杔0b } t644 lapyti dh$Ifgd鬽ibkdv$$If杔0b } t644 lapyti T & ( 6 d  D r $ 0 frXD2gd XD2gdm!{XD2gd纖dgd|o$a$gddwXD2gd'3XD2 H J ^ ` v z    $ & 钲邵邵观й妚bO劼d 7$8$H$^>`劼$gd蘐JXD2gd$%d 7$8$H$^%a$gd$ & F凘勫d 7$8$H$^凘`勫$gd蘐J&>lxs% ; A G k w d!q!! """ ###$$%%i&t&' '()))*@傽嶡B B腂艬镛剔剔剔哗晦剔剔梼梼梼梼梼梼梼梼梼梺梼梼梫hj/OJQJ^JhU&h蘐Jh蘐J5丆JOJQJ^JaJh#h蘐Jh蘐JCJOJQJ^JaJh#hghgCJOJQJ^JaJo( hghgCJOJQJ^JaJ#h蘐Jh蘐J5丆JOJQJ^JaJ h蘐Jh蘐JCJOJQJ^JaJh!5h 5丆JOJQJ^J*"#$%`& ''()z@橝腂艬蹷tCD DDzD鍰凘劺1$XD2^凘`劺d!gdXD2gdXD2gd $凘d 7$8$H$^凘a$gd$ & F凘勫d 7$8$H$^凘`勫$gd蘐Jed software system for analyzing nanopore data. Chinese Science Bulletin, 2014, 59, 4942-4945. (IF = 1.633, Cited by 1) Zhen Gu, Yi-Lun Ying, Bing-Yong Yan*, Hui-Feng Wang*, Pin-Gang He*, Yi-Tao Long. 揈xponentially modified Gaussian relevance to the distributions of translocation events in nanopore-based single molecule detection. Chinese Chemical Letters, 2014, 25, 1029-1032. (IF = 1.587, Cited by 1) 湗蓎荝 ~ 貧^t 鵩uZ 擽ZO&O l毻] 櫉縉沵* 硚s|怱怳SRP[纇KmNOjV髼5uAm>e'YhV鹼邁剉xvz R恎Sf[ 2015 43, 971-976. (IF = 1.529, Cited by 0) ;Nc(Wx褃xy橆v臽礠 1. 齎禰陙6q褃f[鶺褢R梩^褃f[鶺褢y橆v(21505043)  觺魐爛LvY蛓microRNA剉USRP[纇Kmxvz 2016-2018 24.8NCQ ;Nc 2. ,{57yb-N齎ZS隭T褃f[鶺褢y橆v(2013M531138)  鶺嶯硚s|T[剉Y蛓microRNAUSRP[R恎xvz 2015-2016 8N ;Nc N)R 1. 櫉縉沵 擽ZO&O 貧^t 鵩厃 5uAm纇Km艌n蔛5uAm纇Km瘋Gr -N齎 ZL201320572492.20 2. 櫉縉沵 貧^t 鵩uZ 擽ZO&O Ng'YO N蛓硚s|T[IQ5u纇Km甠`l -N齎 ZL201320623353.30 3. 櫉縉沵 ^k 貧^t 擽ZO&O Y梾 Ng}Y顣 鶺嶯梖:Wb螾剉鶹`硚s|怱悇vIQ5u Tek Oa筫誰 -N齎 ZL20150225193.50 4. 櫉縉沵 ^k 貧^t R\R 擽ZO&O N蛓褢^\唹渷硚s|T[粂P[5uAm ce\IQ貧 Tek纇Km艌n -N齎 ZL201520285880.10 f[/gAm;m≧ 93rd Canadian Chemistry Conference and Exhibition,  Nanopore Analysis: Sensing the Conformations of a Single ATP-Binding-Aptamer . 2010, Toronto, Canada. (Oral Presentation) 541st WE-Heraeus-Seminar,  A Stimuli-Responsive Nanopore Based on Photoresponsi艬贐蹷^CbCdCDD DDD$DTDXD擠欴翫艱EEJENE嶦擡蠩訣駿鬍胼温滴兾q蝑蝢蝑蝢蝑蝢蝑蜹hj/h 5丆JOJQJ^Jh]//CJOJQJ^Jo("hj/h5丆JOJQJ\乛J+h!5h5丅*OJPJQJ\乛Jphh!5hOJQJ^Jhj/h CJOJQJ^Jhm!{CJOJQJ^Jo(hm!{CJOJQJ^Jhj/hCJOJQJ^Jh!5h 5丱JQJ^J'h!5h5丅*OJQJ\乛Jph鍰lE鬍鯡FbGwPQ凴頡VS襍許諷赟躍郤釹鍿鑃霺gd-}!$ & F 勪XD2^`勪$gdj/!gdXD2gd XD2gd凘劺1$XD2^凘`劺d鬍鯡﨓FlF G G`GbGHPvP鉖錚鍼Q*R,R@RFR\RbRnRrR胝卡懆憐_]_╛╛╛˙態慱B4hj/hB*CJOJPJQJ\乛JmHphsHU4hj/hiB*CJOJPJQJ\乛JmHphsH,hj/h!5B*CJOJPJQJ\乛Jph,hj/hB*CJOJPJQJ\乛Jph,hj/hiB*CJOJPJQJ\乛Jph+h!5h5丅*OJPJQJ\乛Jph+h!5hi5丅*OJPJQJ\乛Jph'h!5h 5丅*OJQJ\乛Jphve Host-Guest Interactions. 揟ransport through Nanopores: From Understanding to Engineering, 2013, Bremen, Germany. The Biophysical Society 60th Annual Meeting, 揝ingle Nucleotide Discrimination With Electro-Optical Nanopore. 2016, Los Angeles, U.S.A. ,{ NJ\hQ齎u}TR恎Sf[f[/gJTNx▼O,  uir硚s|怱惱hKmUS*NATP8hx怣慡O蔛vQ刧媁豐S . 2010, S琋. (鉙4YJT) ,{ASNJ\hQ齎R恎Sf[t^O,  蛻亯uirRP[剉硚s|怱怳SRP[4ls^纇Km . 2012, R棝\. 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